RPA/RAA Primer Bank

Introduction

RPA/RAA Primer Database is an online, curated database of experimentally validated recombinase polymerase amplification (RPA) primers and recombinase-assisted amplification (RAA) primers. The primers are derived from the literature on the use of RPA or RAA for the diagnosis of the five major syndromes (respiratory pathogens, diarrheal pathogens, febrile with rash pathogens, febrile with hemorrhagic pathogens, and encephalitis and meningitis pathogens).

RPA/RAA Primer Database provides an intuitive, user-friendly interface, implying functions for browsing, searching, grouping, and downloading data that expedite the exploration of experimentally validated RPA/RAA primers from the massively scattered literature, and the comparison of newly designed primers with the published, screened ones.

RPA/RAA Primer Database workflow comprises three steps: literature aggregation, data curation, and database and website implementation. RPA/RAA primers and their respective information were retrieved from the reference literature in the PubMed database, and manually curated into five specified descriptive categories. This resource provides direct links to multiple databases, including PubMed, GenBank, and the NCBI Taxonomy database, as well as to the original publication to fetch more details and facilitate backtracking to the reference studies.

RPA/RAA primer database features

Primers page for browsing all the RPA/RAA primers embedded in the database.
Pathogens page for inspecting pathogens in the database by providing a taxonomic perspective of the target pathogens.
Publications page for presenting all the reference articles that have been investigated to establish the database.

RPA/RAA primer database currently contains

The information provided is for research only and may not be used for clinical decision making or intervention.
Please contact maxj@ivdc.chinacdc.cn for further information.

Contact

RPA/RAA primer database is a project of the National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases. To gain further information, to send feedback,to submit newly validated RPA/RAA primers, or revise the existing data to enhance the integrity of the database, please contact us.

National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases
National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
Head of Laboratory: Dr Xuejun Ma
E-Mail: maxj@ivdc.chinacdc.cn